Experimental model of isolated lung perfusion in rats: technique and application in lung preservation studies* Modelo experimental de perfusão pulmonar isolada em ratos: técnica e aplicações em estudos de preservação pulmonar

نویسندگان

  • Paulo Manuel Pego-Fernandes
  • Eduardo de Campos Werebe
  • Rogério Pazetti
  • Karina Andrighetti de Oliveira
  • Paula Roberta Otaviano Soares
  • Fabio Biscegli Jatene
چکیده

Small animal models are particularly suitable for lung preservation studies, because they are simple and costeffective. This brief communication focuses on the technical description of an ex vivo lung perfusion model in rats by means of a commercially available apparatus, which was the first to be installed in a thoracic surgery research laboratory in Brazil. The model and its preparation, together with its applications for lung preservation studies, are described in detail. All technical details can also be seen in a video posted on the website of the Brazilian Journal of Pulmonology.

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تاریخ انتشار 2010